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Asked 8/4/2008

Does a high hdl offset a high ldl

I am a 63 year old women. The doctor just called with results of my cholesterol test. She said my LDL is 264, my HDL is 84 my total is 265. The fact that my HDL is so good does that offset the fact that my LDL is to high. She wants to put me on meds. I'm not sure. She could not answer this question that is why I am writting to you. thank you, Kathy

 
 
 
 
 
Answers

Answer 1/4 - Submitted 8/4/2008

Total cholesterol is actually an algebraic formula that helps to determin the ratio of LDL to HDL. Total cholesterol = LDL+ HDL + (triglycerides/5). It is because your total cholesterol is over 200 that your doctor would like to put you on medication. Either it is a Statin like Crestor, Lipitor, Lescol, Mevacor, Pravachol, or Zocor. Statins block the production of cholesterol in the liver itself. They lower LDL, the "bad" cholesterol, and triglycerides, and have a mild effect in raising HDL, the "good" cholesterol. Side effects can include intestinal problems, liver damage, and in a few people, muscle tenderness. Another medication class are Nicotinic Acids such as Nicolar and Niaspan. Nicotinic acid is a B-complex vitamin. It's found in food, but is also available at high doses by prescription. It lowers LDL cholesterol and raises HDL cholesterol. The main side effects are flushing, itching, tingling and headache. Then there are Bile Acid Resins such as Questran and Questran Light, Colestid, WelChol. These drugs work inside the intestine, where they bind to bile from the liver and prevent it from being reabsorbed into the circulatory system. Bile is made largely from cholesterol, so these drugs work by depleting the body's supply of cholesterol. The most common side effects are constipation, gas and upset stomach. The last are fibrates which reduce the production of triglycerides and can increase HDL cholesterol. Examples of these are Atromid, Tricor, or Lopid.

The side effects of cholesterol-lowering drugs may include:
Muscle aches (If you develop these, call your doctor immediately), abnormal liver function, allergic reaction (skin rashes), heartburn, dizziness, abdominal pain, constipation, decreased sexual desire, flushing with nicotinic acid.

Hope this helps you understand better what is going on. Good luck, Susu

 
 

Answer 2/4 - Submitted 7/21/2011

My doctor says the answer is no. He said one does not receive the benefits of a high HDL unless the LDL is below 100.

 
 

Answer 3/4 - Submitted 7/21/2011

My doctor says no. He said the benefits of a high HDL do not occur unless the LDL is below 100.

 
 

Answer 4/4 - Submitted 7/21/2011

Dear Oreide277

HDL cholesterol is called good cholesterol, because it prevents lipid deposition inside the arteries. But your LDL cholesterol is pretty high and i do not think your high HDL will offset your high LDL. To minimize the risk of heart disease you need at least less than 200mg/dl LDL cholesterol level. To achieve that i think you need to take drugs.

Statins are the most commonly used drugs.e.g. Lipitor, Crestor. They will reduce your LDL cholesterol levels and increase HDL cholesterol levels. In addition, Lipitor can reduce your triglyceride levels. However, you need to reduce your fat intake. Otherwise these meds would not work.

If you have liver diseases or muscle diseases then tell that to your doctor, before starting on these drugs. They can sometimes cause liver problems and muscle problems. Therefore, your doctor may advice you to test your liver function tests regularly.

Hope this helps

 
 
 
 
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